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Led by Professor David Celermajer
People start to develop the first stages of heart disease quite early in life. But they often only find out they have heart disease when they suffer a life threatening heart attack or stroke. The Clinical Research Group focuses on the early changes that eventually lead to blood vessel hardening and heart disease.
The group looks at the influence of gender, ethnic background, life-style, genetics, obesity, age and other factors which contribute to the development of heart disease. Their quest is to develop a simple blood test or imaging test to diagnose the early stages of the disease. This will revolutionise the way we treat heart disease and prevent millions of deaths worldwide each year.
The group works closely with heart disease patients and people known to be most at risk of developing the disease. These people have greatly helped HRI by participating in heart disease studies. Recently the Clinical Research Group has developed a number of non-invasive techniques, mainly ultrasound based, which detect the development of early stages of vessel abnormalities in the blood circulation system.
The group is also researching the roles of inflammation and cholesterol in heart disease.
Current Projects
Circulating markers of coronary disease- haptoglobin and related molecules.
Obesity Studies in Children
Male Sex Hormones and the Link to Atherosclerosis
Clinical Study of the Indian Community and Heart Disease
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