Dr Xuyu Liu and his team, the Cardiovascular-protective Signalling and Drug Discovery Unit at the Heart Research Institute (HRI), have had phenomenal success with the award of two grants.
Dr Liu was awarded a 2022 Discovery Early Career Researcher Award (DECRA) for his research into ‘Chimeric molecules for precision protein modification’, a project that will invent two new technology platforms to aid the group’s new drug discovery for treating chronic diseases such as cardiovascular disease.
The new technology platforms will engineer proteins within live cells with precision, which will bypass the traditional need for permanent gene editing. The team will learn how protein function, stability, location and activity are influenced by specific modifications – unlocking the know-how of the molecular systems underpinning cell behavioural and functional changes.
As a DECRA Fellow, Dr Xuyu Liu will be working on this project for the next three years, with the potential to create opportunities for commercialisation and add substantial value to the biotechnology and pharmaceutical sectors.
