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Heart disease is one of the world’s biggest killers and current diagnostic methods are inadequate for early disease detection. Molecular-level changes in early heart disease occur on the nanoscale. Bio-inspired by immune cells, we have established a multidisciplinary team from HRI, Science, Medicine and Engineering to build synthetic nanorobots that move around the body to find and identify early stage diseased blood vessels. In this project, we will focus on designing and developing hematological and immunological compatible biomolecular devices by integrating molecular, protein and materials engineering. We will develop sophisticated in vitro microfluidic systems to evaluate biological interactions of nanorobot components and develop novel biomimetic strategies to modulate the biological response.

For more information on PhD projects, please visit our Sydney Nano Grand Challenge website.