Dr Freda Passam leads the Haematology Research Group at the Heart Research Institute/Charles Perkins Centre of The University of Sydney, focused on basic and translational research in thrombotic disease. She is a clinical academic haematologist at the Royal Prince Alfred Hospital, Sydney, with a special interest in thrombosis and haemostasis.
Dr Passam received her medical degree and PhD in Greece. She trained in clinical and laboratory haematology, initially in Greece and then in Sydney, and did postdoctoral thrombosis research at the University of New South Wales (UNSW) and Harvard University. Dr Passam returned to Sydney in 2013 as a haematologist at St George Hospital and Senior Lecturer in Medicine at UNSW.
She is a recipient of the 2017 Sydney Cardiovascular Fellowship, which brings her to The University of Sydney to develop her research program and to RPA Hospital to establish a Thrombosis Clinic dedicated to the management of patients with thrombotic disease. Dr Passam’s research has identified a group of clotting enzymes, named thiol isomerases, that have potential as novel antithrombotic targets. Her research group has detected post-translational modifications of clotting proteins as novel biomarkers of thrombotic disease. The Haematology Research Group also has a keen interest in the application of microfluidic devices for the diagnosis of thrombotic and bleeding tendency in patients.