Imala Alwis

The powerful enzyme Thrombin is by far the most robust activator of platelets and blood clotting (coagulation) in both physiological haemostasis and pathological thrombotic response.

The leading cause of death in people with diabetes is cardiovascular disease, with up to 70% of deaths relating to the development of blood clots supplying the heart (heart attack) or brain (ischemic stroke).

The development of a blood clot in the cerebral circulation (ischaemic stroke) is the third most common cause of death and the most common cause of adult disability globally.

Antithrombotic therapies, which primarily consist of antiplatelet and anticoagulant agents, have become the cornerstone therapies for a wide variety of cardiovascular diseases.