Dr Jaideep Singh

Co-inventor, WO2019/142124A1, Pharmaceutical compositions for treatment of vitiligo.

Co-inventor, US20200179339, Pharmaceutical compositions for treatment of atopic dermatitis.

Co-inventor, IN201921046094, Pharmaceutical compositions for treatment of vitiligo.

Co-inventor, IN202021007941A, Pharmaceutical compositions for treatment of alopecia.

Singh J, Jackson KL, Fang H, Gumanti A, Claridge B, Tang FS, Kiriazis H, Salimova E, Parker AM, Nowell CJ, Woodman OL, Greening DW, Ritchie RH, Head GA, Qin CX. The Novel formylpeptide receptor 1/2 agonist limits hypertension-induced cardiovascular damage. Cardiovascular Research, 2024; 120(11): 1336-1350.

Singh J, Jackson KL, Tang FS, Fu T, Nowell C, Salimova E, Kiriazis H, Ritchie RH, Head GA, Woodman OL, Qin CX. The pro-resolving mediator, annexin A1 regulates blood pressure, and age-associated changes in cardiovascular function and remodeling. Federation of American Societies for Experimental Biology, 2024; 38(3): e23457.

Jelinic M, Jackson KL, O'Sullivan K, Singh J, Giddy T, Deo M, Parry LJ, Ritchie RH, Woodman OL, Head GA, Leo CH, Qin CX. Endothelium-dependent relaxation is impaired in Schlager hypertensive (BPH/2J) mice by region-specific mechanisms in conductance and resistance arteries. Life sciences, 2023; 320: 121542.

Ghoshdastidar K, Patel H, Bhayani H, Patel A, Thakkar K, Patel D, Sharma M, Singh J, Mohapatra J, Chatterjee A. ZYBT1, a potent irreversible Bruton’s tyrosine kinase (BTK) inhibitor that inhibits C481S BTK with profound efficacy against arthritis and cancer. Pharmacology Research & Perspectives, 2020; 8(4): e00565.

Giri P, Delvadia P, Gupta L, Trivedi P, Singh J, Chatterjee A, Srinivas NR. Impact of collagen induced arthritis on the pharmacokinetic disposition of voriconazole, a widely used antifungal agent: in vitro and in vivo investigations in DBA/1J mice. Xenobiotica, 2019; 49(6): 698-707.

Sunil V, Verma MK, Oommen AM, Sadasivuni M, Singh J, Vijayraghav DN, Chandravanshi B, Shetty J, Biswas S, Dandu A, Moolemath Y, Venkataranganna MV, Somesh BP, Jagannath MR. CNX-011-67, a novel GPR40 agonist, enhances glucose responsiveness, insulin secretion and islet insulin content in n-STZ rats and in islets from type 2 diabetic patients. BMC Pharmacology and Toxicology, 2014; 15: 19.

Anil TM, Dandu A, Harsha K, Singh J, Shree N, Kumar VS, Lakshmi MN, Sunil V, Harish C, Balamurali GV, Naveen Kumar BS, Gopala AS, Pratibha S, Sadasivuni M, Anup MO, Moolemath Y, Venkataranganna MV, Jagannath MR, Somesh BP. A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits. BMC Pharmacology and Toxicology, 2014; 15: 43.

Sadasivuni MK, Reddy BM, Singh J, Anup MO, Sunil V, Lakshmi MN, Yogeshwari S, Chacko SK, Pooja TL, Dandu A, Harish C, Gopala AS, Pratibha S, Naveenkumar BS, Pallavi PM, Verma MK, Moolemath Y, Somesh BP, Venkataranganna MV, Jagannath MR. CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridemia, hepatomegaly and body weight gain in animal models. Diabetology & Metabolic Syndrome, 2014; 6: 83.

Sadasivan SK, Vasamsetti B, Singh J, Siddaraju N, Khan KM, Oommen AM, Jagannath MR, Rao RP. Modulation of de novo purine biosynthesis leads to activation of AMPK and results in improved glucose handling and insulin sensitivity. Journal of Diabetes & Metabolic Disorders, 2014; 13: 51.

Sadasivan SK, Vasamsetti B, Singh J, Marikunte VV, Oommen AM, Jagannath MR, Pralhada Rao R. Exogenous administration of spermine improves glucose utilization and decreases bodyweight in mice. European Journal of Pharmacology, 2014; 729: 94-99.

Gowda N, Dandu A, Singh J, Biswas S, Raghav V, Lakshmi MN, Shilpa PC, Sunil V, Reddy A, Sadasivuni M, Aparna K, Verma MK, Moolemath Y, Anup MO, Venkataranganna MV, Somesh BP, Jagannath MR. Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats. BMC Pharmacology and Toxicology, 2013; 14: 28.

Singh J, Samir C. Pharmacokinetic changes of Fluvoxamine and Pioglitazone by drug interaction in healthy, diabetic, and depressive rats. International Journal of Pharmacy and Pharmaceutical Sciences, 2013; 5(1): 352-355.

Singh J, Samir C. Influence of Esomeprazole on the pharmacokinetic and pharmacodynamic properties of glipizide in normal and diabetic guinea pigs. Indo American Journal of Pharmaceutical Research, 2012; 2: 10.

Banji D, Singh J, Banji OJ, Shanthamurthy M. Scrutinizing the aqueous extract of leaves of Pedalium murex for the antiulcer activity in rats. Pakistan Journal of Pharmaceutical Sciences, 2010; 23(3): 295-299.

Babitha S, Ramesh B, Singh J. A study on drug-drug interaction of Pantoprazole with Glipizide in rabbits. Pharmacologyonline, 2009; 2: 667-672.

Melbourne scientists reveal potential new therapy for organ damage caused by high blood pressure

Compelling new insights point to natural treatment for age-related cardiovascular disease