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About
- Meet the Director of Cardiovascular Research and Senior Management
- Meet the Board
- Facilities
- History
- Partners
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Research Group Leaders
- Professor David Celermajer
- Dr Melissa Farnham
- Professor Ben Freedman OAM
- Distinguished Professor Annemarie Hennessy AM
- Professor Shaun Jackson
- Dr Mary Kavurma
- Dr Xuyu Liu
- Dr Ashish Misra
- Dr Christopher Stanley
- Professor Roland Stocker
- Dr John O'Sullivan
- Dr Freda Passam
- Associate Professor Sanjay Patel
- Dr Anna Waterhouse
- Reports
- FAQs
- Tour the Institute
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Our Research
- Microvascular Research
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Arterial Inflammation and Redox Biology
- The role of bilirubin in cardiovascular and metabolic diseases
- Improving our ability to identify individuals at high risk of suffering a heart attack
- Examining the role of extracellular myeloperoxidase in the pathogenesis, identification and treatment of high-risk unstable and ruptured atherosclerotic plaque
- Regulation of cell-to-cell communication during inflammation by tryptophan-derived cis-WOOH
- Overcoming CoQ deficiencies in cardiovascular and metabolic diseases by modulating endogenous regulators of CoQ synthesis
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Cardiovascular-protective Signalling and Drug Discovery
- Chemical knock-out of proteins in primary leukocytes using PROTAC-based modulators
- Towards the development of more effective and safer high-affinity ACE2 variants for the treatment of COVID-19
- Chemical synthesis and phenotypic validation of precision PROTACs for cancer and cardiovascular disease
- Understanding heart-healthy diets at the molecular level
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Cardiometabolic Disease
- Uncovering the interaction of obstructive sleep apnoea with cardiac metabolism, function, and disease
- Developmental and dietary origins of myocardial disease
- Transforming diagnosis and treatment of stiff heart failure
- Dietary-microbiome-metabolic interactions in cardiovascular disease
- Leveraging cardiac substrates to improve cardiac energetics and outcomes in HFpEF
- A key metabolic switch in cardiometabolic disease
- Vascular Immunology
- Vascular Complications
- Cardiovascular Neuroscience
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Coronary Diseases
- Determining the effects of colchicine on smooth muscle cell plasticity in advanced atheroma
- Determining the anti-atherosclerotic properties of TRAIL
- Effects of colchicine on metabolomic profiles in coronary disease patients
- Effects of colchicine on miRNA levels in coronary disease patients
- Effects of colchicine on prognostically significant vascular endpoints in patients post-acute coronary syndrome (ACS)
- Effects of colchicine on neutrophil function in acute coronary syndrome (ACS) patients
- Salutary effects of colchicine in a murine model of type 2 diabetes
- The effects of colchicine on the development and regression of atherosclerosis
- The effects of colchicine on immune cell migration in acute coronary syndrome patients
- Cardiovascular Medical Devices
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Thrombosis
- Developing a novel preclinical ischaemic stroke model
- Understanding the mechanisms leading to microvascular dysfunction and poor cerebral perfusion in stroke
- Developing safer anti-clotting agents derived from “Mother Nature”
- Biomechanical sensing and blood clot formation: Solving a sticky clotting problem in diabetes
- Developing novel approaches to the treatment of ischaemic stroke
- Platelet death as an important regulator of blood clot formation
- “Bad Blood”: Unravelling the link between gut ischemia and remote organ injury
- Haematology Research
- Atherosclerosis and Vascular Remodelling
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Clinical Research
- Optimising exercise prescription and delivery in congenital heart disease – The Congenital Heart Fitness Intervention Trial: CH-FIT
- Australian-wide study of the outcomes and burden of congenital heart disease across the life-course
- Improving health outcomes in congenital heart disease for young adults, their families and the health system
- Young adults with congenital heart disease
- Early detection of pulmonary vascular disease
- Detecting heart attacks
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Heart Rhythm and Stroke Prevention
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News
- Groundbreaking world-first trial offers new hope to stroke sufferers
- Dr Jessica Maclean awarded THANZ grant
- Dr Ashish Misra awarded second Perpetual IMPACT grant
- Save the date: Sydney Cardiovascular Symposium, 9 – 10 Dec 2021
- World’s largest screening project to launch in Australia to prevent disabling strokes
- When irregular heartbeat is something more: the WHF Roadmap on Atrial Fibrillation
- Dr Melissa Farnham awarded Kirby Foundation grant
- Australian research to help prevent 10 Australians dying of heart attack each day faces a funding shortfall
- First Nations peoples at earlier risk of atrial fibrillation
- View news archives
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Health
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Your health
- Core strength: why is it important and how do you maintain it?
- How to manage food intolerances
- How to return to exercise after a cardiac event or diagnosis
- A paramedic’s perspective on heart attacks
- 7 tips for fussy eaters
- Creamy chicken pesto pasta
- Chicken and vegetable soup
- Beef and barley stew
- Banana and berry bran muffins
- View health archives
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Learn
- Thrombosis
- Atherosclerotic plaque
- Acute coronary syndrome
- Congenital heart disease
- Obstructive sleep apnoea
- High blood pressure
- Inactivity and a sedentary lifestyle
- Alcohol
- Smoking
- Obesity and overweight
- High cholesterol
- Heart failure
- Heart attack
- Atherosclerosis
- Stroke
- Risk factors for cardiovascular disease
- Women and heart disease
- Preeclampsia
- Diabetes
- Peripheral artery disease
- Atrial fibrillation
- Cardiovascular disease
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Your health
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Stories
- Have a story you’d like to share?
- Maryanne's story
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- Liesl’s story
- Phil's story
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- John's story
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- Jake's story
- Alistair's story
- Kerri's story
- Beverley's story
- Laura's story
- Renee's story
- Faye's story
- Greg and Jo's story
- Cara's story
- Basil and Siana's story
- Jason's story
- Phil's story
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Join Us
- Why Work at HRI?
- Benefits
- Student Opportunities
- Summer Scholarships
- Postdoctoral and Fellowship Opportunities
- Jobs Available
- HRI Careers Newsletter
- Our Stories - Life at HRI
- Jessica Maclean’s advice for a career in medical research
- Melissa Farnham's career in medical research
- Xuyu Liu's advice for a career in medical research
- Manisha Patil's career in medical research
- Dr Yen Chin Koay's video transcript about her career at HRI.
- HRI Open Day
- Summer Scholars
- High School Students' Work Experience
- New Zealand Research Assistant to PhD Pathways Program
- Contact
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