- About
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Our Research
- Microvascular Research Group
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Arterial Inflammation and Redox Biology Group
- The role of bilirubin in cardiovascular and metabolic diseases
- Improving our ability to identify individuals at high risk of suffering a heart attack
- Examining the role of extracellular myeloperoxidase in the pathogenesis, identification and treatment of high-risk unstable and ruptured atherosclerotic plaque
- Regulation of cell-to-cell communication during inflammation by tryptophan-derived cis-WOOH
- Overcoming CoQ deficiencies in cardiovascular and metabolic diseases by modulating endogenous regulators of CoQ synthesis
- Cardiovascular-protective Signalling and Drug Discovery
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Cardiometabolic Disease
- Novel therapeutic strategies in type 2 diabetes
- Dietary-microbiome-metabolic interactions in cardiovascular disease
- Leveraging cardiac substrates to improve cardiac energetics and outcomes in diabetic cardiomyopathy and HFpEF
- Targeted therapy in type 2 diabetes
- A key metabolic switch in cardiometabolic disease
- Novel pathways in ischaemic heart disease
- Vascular Immunology
- Vascular Complications
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Coronary Diseases
- Determining the effects of colchicine on smooth muscle cell plasticity in advanced atheroma
- Determining the anti-atherosclerotic properties of TRAIL
- Effects of colchicine on metabolomic profiles in coronary disease patients
- Effects of colchicine on miRNA levels in coronary disease patients
- Effects of colchicine on prognostically significant vascular endpoints in patients post-acute coronary syndrome (ACS)
- Effects of colchicine on neutrophil function in acute coronary syndrome (ACS) patients
- Salutary effects of colchicine in a murine model of type 2 diabetes
- The effects of colchicine on the development and regression of atherosclerosis
- The effects of colchicine on immune cell migration in acute coronary syndrome patients
- Cardiovascular Medical Devices
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Thrombosis
- Developing a novel preclinical ischaemic stroke model
- Understanding the mechanisms leading to microvascular dysfunction and poor cerebral perfusion in stroke
- Developing safer anti-clotting agents derived from “Mother Nature”
- Biomechanical sensing and blood clot formation: Solving a sticky clotting problem in diabetes
- Developing novel approaches to the treatment of ischaemic stroke
- Platelet death as an important regulator of blood clot formation
- “Bad Blood”: Unravelling the link between gut ischemia and remote organ injury
- Haematology Research
- Atherosclerosis and Vascular Remodelling
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Clinical Research
- Optimising exercise prescription and delivery in congenital heart disease – The Congenital Heart Fitness Intervention Trial: CH-FIT
- Australian-wide study of the outcomes and burden of congenital heart disease across the life-course
- Improving health outcomes in congenital heart disease for young adults, their families and the health system
- Young adults with congenital heart disease
- Early detection of pulmonary vascular disease
- Detecting heart attacks
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Heart Rhythm and Stroke Prevention
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News
- Dr John O’Sullivan – 2020 Future Leader Fellowship
- Dr Lining (Arnold) Ju – Eureka Prize Finalist
- World-first study shows smartphones can improve detection rate of atrial fibrillation in patients following stroke
- Dr Melissa Farnham awarded Diabetes Australia grant
- HRI sheds further light on relationship between diet and cardiometabolic disease
- HRI study confirms role of GPs and novel eHealth tools for AF screening to prevent stroke
- Dr Lining (Arnold) Ju – Young Tall Poppy Science Award
- Dr Mary Kavurma awarded ACvA Research Catalyst Grant
- Dr Ashish Misra awarded Perpetual IMPACT grant
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Health
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Your health
- Prepping healthy, budget-friendly food
- 3 simple things to take care of your heart health
- How to help your body recover after exercise
- Extra hygiene precautions won't weaken our immune systems
- Top 7 superfoods to try
- Which face mask should I wear?
- 4 unusual things we’ve learned about the coronavirus since the start of the pandemic
- How to set up your own exercise program
- Managing iron levels
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Learn
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- Dr Yen Chin Koay's video transcript about her career at HRI.
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COVID-19
HRI breakthrough treatment for blood clots in COVID-19 patients
HRI breakthrough for COVID-19 patients
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