Vascular Complications.

Our mission is to understand fundamental mechanisms in molecular and cellular biology leading to cardiovascular diseases.

The end goal of our studies is to develop more effective treatments for the debilitating conditions associated with vascular complications.

What impact will this research have?

The Vascular Complications Group focuses on understanding the pathogenesis of atherosclerosis and cardiovascular disease (CVD). We use multiple models, genetic manipulation, biochemical and molecular biology tools to dissect how blood vessels become dysregulated, with particular emphasis on changes to transcriptional regulation, vascular cell adaptation and function, under normal and abnormal settings in the blood vessel wall.  Our recent work has focused on identifying protective mechanism(s) of specific genes, which have opened new opportunities for developing novel therapeutic interventions. We also ask critical questions underlying pathogenesis of obesity, diabetes and kidney disease, which are complications of CVD.

Dr Mary Kavurma
Research group led by:
Research covers areas of:
What’s new in the lab?

Mentoring the next generation of scientists

Recently, ten bright young researchers from New Zealand took part in a summer scholarship at the HRI to get hands-on experience in our world-class laboratory facilities and to be mentored by leaders in the cardiovascular disease research field. They share their experiences here.
Current team update

Dr Siân Cartland has been awarded a Sydney Medical School Early Career Research Grant.

Sep 08, 2015

Meet the team

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